Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288779 | 0.91 | GPR34 (0.53) | ALDH1A1MEN1LMNAKMT2ACTSL | |
| Triletide SCHEMBL11761127 | 0.87 | ALDH1A1 (0.52) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Triletide SCHEMBL9551361 | 0.87 | ALDH1A1 (0.52) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Triletide SCHEMBL27342204 | 0.87 | ALDH1A1 (0.52) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL27342815 | 0.86 | ALDH1A1 (0.53) | ALDH1A1LMNATHRBCYP2C9CYP2C19 | |
| SCHEMBL9551271 | 0.86 | ALDH1A1 (0.53) | ALDH1A1LMNATHRBCYP2C9CYP2C19 | |
| SCHEMBL10436049 | 0.86 | ALDH1A1 (0.53) | ALDH1A1LMNATHRBCYP2C9CYP2C19 | |
| SCHEMBL27352065 | 0.86 | BIRC2 (0.52) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9551368 | 0.85 | CTSL (0.54) | ALDH1A1CTSL | |
| SCHEMBL9551274 | 0.85 | CTSL (0.54) | ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |