Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7301902 | 0.87 | ALOX15 (0.52) | ALOX15DRD1ADRB2ADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL7300561 | 0.85 | ALOX15 (0.50) | ALOX15DRD1ADRB2ADRA2ADRD2 | |
| SCHEMBL21510392 | 0.83 | TACR1 (0.50) | ALOX15DRD1ADRB2ADRA2ADRD2 | |
| Hydrochloric Acid SCHEMBL7294546 | 0.79 | ALDH1A1 (0.44) | ALOX15DRD1ALDH1A1KMT2APOLB | |
| SCHEMBL1069133 | 0.76 | ALOX15 (0.44) | ALOX15DRD1ADRB2ADRA2ADRD2 | |
| SCHEMBL26017394 | 0.75 | DRD1 (0.49) | ALOX15DRD1ADRB2ADRA2ADRD2 | |
| SCHEMBL3282594 | 0.75 | TACR1 (0.53) | ALDH1A1TACR1POLB | |
| SCHEMBL6224832 | 0.75 | TACR1 (0.53) | ALDH1A1TACR1POLB | |
| SCHEMBL23417656 | 0.74 | ALOX15 (0.49) | ALOX15DRD1ALDH1A1TACR1KMT2A | |
| SCHEMBL25471910 | 0.73 | ALDH1A1 (0.49) | ALOX15ALDH1A1TACR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352815-B1 | PRODRUGS OF DOPAMINE | ZAMBON GROUP S.p.A. (IT) | 1993-05-19 | — | — | EP | disclosed |
| US-5013753-A | Prodrugs of dopamine | SIMES (IT) | 1991-05-07 | — | — | US | disclosed |
| EP-0352815-A1 | Prodrugs of dopamine | ZAMBON GROUP S.p.A. (IT) | 1990-01-31 | — | — | EP | disclosed |