Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659770 | 0.95 | PTGS1 (0.53) | LCKTACR1PTGS1ALDH1A1MEN1 | |
| SCHEMBL6659765 | 0.95 | PTGS1 (0.53) | LCKTACR1PTGS1ALDH1A1MEN1 | |
| SCHEMBL21510392 | 0.90 | TACR1 (0.50) | ALOX15TACR1PTGS1ALDH1A1DRD1 | |
| SCHEMBL13481269 | 0.88 | ALOX15 (0.46) | ALOX15LCKPTGS1HDAC1HDAC6 | |
| SCHEMBL1067908 | 0.88 | ALOX15 (0.46) | ALOX15LCKPTGS1KMT2AHDAC1 | |
| SCHEMBL25471843 | 0.88 | ITGB3 (0.49) | ALOX15TACR1PTGS1ALDH1A1DRD1 | |
| SCHEMBL1069987 | 0.87 | OPRK1 (0.49) | ALOX15LCKPTGS1ALDH1A1HDAC1 | |
| SCHEMBL22290230 | 0.87 | OPRK1 (0.49) | ALOX15LCKPTGS1ALDH1A1HDAC1 | |
| Hydrochloric Acid SCHEMBL11446868 | 0.87 | ALOX15 (0.45) | ALOX15LCKPTGS1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11445444 | 0.86 | OPRK1 (0.48) | ALOX15LCKPTGS1ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210154213-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OCULAR DISEASES | CALASIA PHARMACEUTICALS INC (US) | 2021-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154213-A1 | PHARMACOLOGICAL AGENTS FOR TREATING OCULAR DISEASES | CRYAA, CRYAB, TTR | ALOX15 1497/4885LCK 4691/4885TACR1 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.