Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302982 | 0.83 | PREP (0.54) | PREPLMNARAB9ASMN1; SMN2PKM | |
| SCHEMBL9814597 | 0.75 | ACE (0.56) | PREPRAB9AALDH1A1ACENPC1 | |
| SCHEMBL7297458 | 0.74 | PREP (0.72) | PREPLMNAALDH1A1ACEMAPK1 | |
| SCHEMBL7435975 | 0.73 | PREP (0.59) | PREP | |
| SCHEMBL7292870 | 0.73 | PREP (0.53) | PREPRAB9ASMN1; SMN2ALDH1A1DPP4 | |
| SCHEMBL7302245 | 0.73 | PREP (0.38) | PREPDPP4 | |
| SCHEMBL9814639 | 0.72 | ACE (0.56) | RAB9AALDH1A1ACENPC1 | |
| SCHEMBL7303343 | 0.72 | PREP (0.56) | PREPSMN1; SMN2ALDH1A1ACE | |
| SCHEMBL5491765 | 0.71 | LMNA (0.54) | LMNARAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL6882664 | 0.71 | LMNA (0.54) | LMNARAB9ASMN1; SMN2PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372484-B1 | Condensed benzene derivative | ZERIA PHARM CO LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5028604-A | Cognition Activators | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0372484-A2 | Condensed benzene derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |