SCHEMBL7302245

SCHEMBL7302245

COc1cc2c(cc1C)CC(CCCCCC(=O)N1CCCCC1C(=O)N1CCC[C@H]1C=O)=C2

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.38
HTR1A P08908 3/20 0.37
HTR7 P34969 3/20 0.37
CPT2 P23786 1/20 0.36
CPT1A P50416 1/20 0.36
SPHK1 Q9NYA1 1/20 0.33
HTR2A P28223 1/20 0.33
HTR6 P50406 1/20 0.33
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7435975 0.80 PREP (0.59) PREP
SCHEMBL7293107 0.73 PREP (0.43) PREPDPP4
SCHEMBL7301873 0.69 PREP (0.76) PREP
SCHEMBL7302982 0.68 PREP (0.54) PREPHTR1AHTR7
SCHEMBL7294659 0.68 PREP (0.55) PREP
SCHEMBL7292436 0.67 PREP (0.57) PREP
SCHEMBL7294125 0.67 PREP (0.75) PREP
SCHEMBL7292875 0.66 ALDH1A1 (0.46) PREP
SCHEMBL8153242 0.66 MEN1 (0.55) PREP
SCHEMBL8153245 0.66 MEN1 (0.55) PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed