Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.48 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274240 | 0.88 | MAPT (0.52) | ITGB3ITGA2BST14LMNASMN1; SMN2 | |
| SCHEMBL7303187 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BEPHX2NR1H4ST14 | |
| SCHEMBL7303301 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BEPHX2NR1H4ST14 | |
| Iodide SCHEMBL9261540 | 0.87 | MAPT (0.51) | ITGB3ITGA2BST14LMNASMN1; SMN2 | |
| SCHEMBL7297922 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BMRGPRX1ALDH1A1KMT2A | |
| SCHEMBL7293128 | 0.86 | ITGB3 (0.54) | ITGB3ITGA2BMRGPRX1ALDH1A1KMT2A | |
| SCHEMBL5037627 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BEPHX2NR1H4ST14 | |
| SCHEMBL7303302 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2BEPHX2NR1H4ST14 | |
| SCHEMBL9272405 | 0.81 | ITGB3 (0.66) | ITGB3ITGA2BEPHX2NR1H4ST14 | |
| SCHEMBL7393093 | 0.81 | AKR1B1 (0.55) | EPHX2NR1H4LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | claimed |
| EP-0680341-A1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMACEUTICALS, INC. (US) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994016739-A1 | PHASE SHIFT COLLOIDS AS ULTRASOUND CONTRAST AGENTS | SONUS PHARMACEUTICALS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |
| US-5256812-A | Antitumor agents, cardiovascular disorders; having amidino or guandino groups | HOFFMANN-LA ROCHE INC. (US) | 1993-10-26 | — | — | US | disclosed |