Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303187 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BEPHX2NR1H4LMNA | |
| SCHEMBL7293149 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BEPHX2NR1H4LMNA | |
| SCHEMBL9269532 | 0.88 | MAPT (0.54) | ITGB3ITGA2BLMNANPC1SMN1; SMN2 | |
| SCHEMBL7302582 | 0.88 | MAPT (0.54) | ITGB3ITGA2BLMNANPC1SMN1; SMN2 | |
| Acetic Acid SCHEMBL9274305 | 0.87 | NPC1 (0.51) | ITGB3ITGA2BLMNANPC1SMN1; SMN2 | |
| SCHEMBL5037627 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BEPHX2NR1H4LMNA | |
| Hydrochloric Acid SCHEMBL9273979 | 0.87 | MAPT (0.53) | ITGB3ITGA2BLMNANPC1SMN1; SMN2 | |
| SCHEMBL7442551 | 0.86 | PRSS1 (0.61) | ITGB3ITGA2BEPHX2NR1H4LMNA | |
| SCHEMBL7122825 | 0.82 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL11787869 | 0.81 | EPHX2 (0.56) | ITGB3ITGA2BEPHX2NR1H4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381033-B1 | Carboxylic-acid and sulphonic-acid amides | HOFFMANN LA ROCHE (CH) | 1994-03-23 | — | — | EP | claimed |