Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045302 | 0.94 | DGKA (0.45) | DGKATSHRLMNAF7F3 | |
| SCHEMBL667189 | 0.91 | CES1 (0.42) | CES1CES2DGKATSHRLMNA | |
| SCHEMBL133540 | 0.91 | ALDH1A1 (0.46) | CES1CES2DGKATSHRLMNA | |
| SCHEMBL10889536 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 | |
| SCHEMBL10892398 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 | |
| SCHEMBL5930620 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 | |
| SCHEMBL17440355 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 | |
| SCHEMBL21956085 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 | |
| SCHEMBL11266899 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 | |
| SCHEMBL8812664 | 0.88 | DGKA (0.53) | DGKATSHRLMNAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |