Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285807 | 0.80 | KDM4E (0.56) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL7283679 | 0.73 | MAPT (0.46) | ALDH1A1KDM4EHPGDRAB9ATUBB4A | |
| SCHEMBL7294168 | 0.73 | CYP1A1 (0.53) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL7294180 | 0.73 | CYP1A1 (0.53) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL27480265 | 0.71 | KDM4E (0.46) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL16536004 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL16536963 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL7281288 | 0.69 | KDM4E (0.44) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL16536117 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDTSHRRAB9A | |
| SCHEMBL7283899 | 0.68 | PDE3B (0.42) | KDM4ETSHRRAB9ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | claimed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |