Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729000 | 0.86 | ADORA3 (0.41) | ADORA3ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL731042 | 0.78 | MAPT (0.47) | ADORA3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5512657 | 0.76 | CHEK1 (0.46) | ADORA3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL728888 | 0.74 | ADORA3 (0.41) | ADORA3ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1895662 | 0.74 | ALDH1A1 (0.44) | ADORA3ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL733655 | 0.72 | KDM4E (0.53) | ADORA3ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1896422 | 0.69 | ALDH1A1 (0.43) | ADORA3ALDH1A1MEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL728945 | 0.69 | HSD17B10 (0.40) | MAPTALDH1A1HPGDKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL730878 | 0.69 | HSD17B10 (0.40) | MAPTALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL728568 | 0.67 | ADORA3 (0.47) | ADORA3ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138173-B2 | Pyrazolo[3,4-C]quinolines, pyrazolo[3,4-C]naphthyridines, analogs thereof, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-03-20 | — | — | US | disclosed |