Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295927 | 0.82 | F2 (0.49) | F2PLGCTRB1CASP1PRCP | |
| SCHEMBL7295597 | 0.82 | F2 (0.48) | F2PLGCTRB1CASP1CMA1 | |
| SCHEMBL7302872 | 0.80 | ACE (0.44) | F2PLGCTRB1CASP1PRCP | |
| SCHEMBL7294595 | 0.80 | KMT2A (0.45) | F2PLGCTRB1CASP1PRCP | |
| SCHEMBL10725371 | 0.78 | F2 (0.54) | F2PLGCTRB1PRSS1 | |
| SCHEMBL7298055 | 0.78 | F2 (0.61) | F2PLGCTRB1CASP1PRCP | |
| SCHEMBL7297974 | 0.77 | ACE (0.42) | F2PLGCTRB1CASP1PRCP | |
| SCHEMBL7304387 | 0.77 | ACE (0.46) | F2PLGCTRB1CASP1PRCP | |
| SCHEMBL7264615 | 0.76 | ACE (0.52) | CTRB1ACEACE2SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL7266302 | 0.76 | F2 (0.51) | F2PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185390-A2 | Tripeptidyl-argininaldehyde, process for its preparation and medicaments thereof, as well as N-(monoalkyl) and N,N-di-(alkyl)-Xxx-L-proline dipeptide | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-06-25 | — | — | EP | disclosed |