Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277970 | 1.00 | KMT2A (0.45) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL9223972 | 0.84 | KDM4E (0.44) | KMT2AKDM4EMEN1 | |
| SCHEMBL2295759 | 0.82 | KMT2A (0.49) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL5709588 | 0.82 | KMT2A (0.49) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL7301131 | 0.82 | KMT2A (0.49) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL7433845 | 0.81 | KDM4E (0.45) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL7433838 | 0.81 | KDM4E (0.45) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL11981992 | 0.81 | REN (0.48) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL7277978 | 0.81 | KDM4E (0.49) | KMT2AKDM4EMEN1ALDH1A1TSHR | |
| SCHEMBL13840602 | 0.81 | REN (0.48) | KMT2AKDM4EMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |