Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.69 |
| ▸ | NPC1 | O15118 | 10/20 | 0.69 |
| ▸ | TP53 | P04637 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293363 | 1.00 | RAB9A (0.69) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL2814428 | 0.84 | KMT2A (0.60) | RAB9ANPC1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL7304276 | 0.84 | NPC1 (0.81) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7301192 | 0.84 | NPC1 (0.81) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL6799157 | 0.83 | RAB9A (1.00) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7301443 | 0.82 | RAB9A (0.71) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL13930992 | 0.82 | RAB9A (0.71) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7300709 | 0.82 | RAB9A (0.71) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL6558299 | 0.80 | KDM4E (0.65) | TP53SMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL989033 | 0.80 | TAAR1 (0.56) | RAB9ANPC1ALOX15ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |