Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.71 |
| ▸ | NPC1 | O15118 | 9/20 | 0.71 |
| ▸ | TP53 | P04637 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300709 | 1.00 | RAB9A (0.71) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7304276 | 0.85 | NPC1 (0.81) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7301192 | 0.85 | NPC1 (0.81) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL2814444 | 0.85 | KMT2A (0.62) | RAB9ANPC1TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL6799157 | 0.84 | RAB9A (1.00) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL29756028 | 0.84 | MAPT (0.59) | RAB9ANPC1ALOX15ALDH1A1LMNA | |
| SCHEMBL30341896 | 0.83 | RAB9A (0.89) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7293363 | 0.82 | RAB9A (0.69) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL7295293 | 0.82 | RAB9A (0.69) | RAB9ANPC1TP53SMN1; SMN2ALOX15 | |
| SCHEMBL11462217 | 0.80 | RAB9A (0.83) | RAB9ANPC1TP53SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |