Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 1/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13576560 | 0.94 | MEN1 (0.88) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9329754 | 0.90 | MEN1 (0.85) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8710919 | 0.87 | MEN1 (0.80) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9800017 | 0.85 | GAA (0.77) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL11572673 | 0.85 | MEN1 (0.76) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6795867 | 0.84 | MEN1 (0.85) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL13698359 | 0.84 | MEN1 (0.91) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL9799681 | 0.84 | MEN1 (0.79) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL11761506 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL1336235 | 0.83 | MEN1 (0.74) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |