Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305251 | 0.86 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325717 | 0.86 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325748 | 0.86 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325670 | 0.86 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL3246823 | 0.85 | SIGMAR1 (0.73) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL3257338 | 0.85 | ALDH1A1 (0.77) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL3253612 | 0.83 | SIGMAR1 (0.71) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL7303032 | 0.83 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL7304070 | 0.82 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325719 | 0.82 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |