Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295692 | 0.83 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL7305251 | 0.83 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325748 | 0.78 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325717 | 0.78 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325670 | 0.78 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL7300222 | 0.77 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1HSD17B10RAB9AL3MBTL1 | |
| SCHEMBL108678 | 0.77 | KDM4E (0.70) | HSD17B10HTR1ATSHRUSP2KDM4E | |
| SCHEMBL2316901 | 0.76 | CYP2D6 (0.82) | ALDH1A1HSD17B10HTR1ATSHRUSP2 | |
| SCHEMBL7304070 | 0.74 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A | |
| SCHEMBL12325719 | 0.74 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1HSD17B10RAB9AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |