Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | PLAU | P00749 | 1/20 | 0.62 |
| ▸ | PLAT | P00750 | 1/20 | 0.62 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652172 | 0.89 | BRAF (0.60) | KCNK9TP53F2PLGPLAU | |
| SCHEMBL4254168 | 0.87 | TP53 (0.80) | KCNK9TP53KCNK3SMN1; SMN2MAPT | |
| SCHEMBL9640342 | 0.87 | PLAU (0.66) | KCNK9TP53F2PLGPLAU | |
| SCHEMBL21620321 | 0.86 | CYP1A2 (0.66) | KCNK9TP53F2PLGPLAU | |
| SCHEMBL23367928 | 0.85 | RAB9A (0.75) | KCNK9TP53F2PLGPLAU | |
| SCHEMBL12201930 | 0.85 | KCNK9 (0.74) | KCNK9TP53PLAUKCNK3SMN1; SMN2 | |
| SCHEMBL7294862 | 0.84 | TRPV1 (0.68) | TP53SMN1; SMN2MAPTHDAC3HDAC8 | |
| SCHEMBL7295349 | 0.84 | MAPT (0.72) | KCNK9TP53PLAUKCNK3SMN1; SMN2 | |
| SCHEMBL13989073 | 0.82 | PLAU (0.55) | TP53F2PLGPLAUPLAT | |
| SCHEMBL13988821 | 0.82 | PLAU (0.55) | KCNK9TP53F2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | KCNK9 2816/4885TP53 3378/4885F2 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.