Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772351 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL8200154 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL27751551 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL27772342 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL8200117 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL8204698 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL8200101 | 0.98 | MAPT (0.49) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL8200303 | 0.94 | MAPT (0.44) | MAPTCYP3A4CYP2D6FAAHNAAA | |
| SCHEMBL1447729 | 0.85 | MAPT (0.38) | MAPTCYP3A4CYP2D6ALDH1A1NPC1 | |
| SCHEMBL6867759 | 0.79 | TNNC1 (0.48) | MAPTCYP3A4CYP2D6FAAHNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101467276-A | Liquid crystalline rylene tetracarboxylic acid derivatives and use thereof | MAX PLANCK GESELLSCHAFT (DE) | 2009-06-24 | — | — | CN | disclosed |
| US-6043227-A | C11 carbamates of macrolide antibacterials | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |