Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19411917 | 0.85 | LMNA (0.32) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL699245 | 0.83 | LMNA (0.31) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL338867 | 0.73 | GABRA1 (0.46) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL25547481 | 0.73 | GABRA1 (0.37) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL26345761 | 0.73 | GABRA1 (0.37) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL145914 | 0.71 | GABRA1 (0.36) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL18948477 | 0.70 | HTT (0.33) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL23202783 | 0.70 | GABRA1 (0.43) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL3234036 | 0.70 | GABRA1 (0.43) | LMNAGABRA1GABRB2TRPA1PTGS1 | |
| SCHEMBL23202734 | 0.70 | GABRA1 (0.43) | LMNAGABRA1GABRB2TRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101367825-A | Double-carbene clamp type rareearth complexes, preparation method and uses of the same in cis-1,4 selective polymerization of diolefin | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-02-18 | — | — | CN | claimed |
| CN-101696208-B | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with a cyclic amino group as CRF antagonists | TAISHO PHARMACEUTICAL CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-101367825-B | Double-carbene clamp type rareearth complexes, preparation method and uses of the same in cis-1,4 selective polymerization of diolefin | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2012-02-08 | — | — | CN | disclosed |
| CN-101367825-A | Double-carbene clamp type rareearth complexes, preparation method and uses of the same in cis-1,4 selective polymerization of diolefin | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-02-18 | — | — | CN | disclosed |
| CN-1692115-A | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2005-11-02 | — | — | CN | disclosed |
| EP-0835257-B1 | INTERMEDIATES AND PROCESS FOR THE MANUFACTURE OF CAMPTOTHECIN DERIVATIVES (CPT-11) AND RELATED COMPOUNDS | UPJOHN CO (US) | 2002-09-25 | — | — | EP | disclosed |
| US-6444820-B1 | ANTICARCINOGENIC AGENTS | HENEGAR KEVIN E (US) | 2002-09-03 | — | — | US | disclosed |
| US-6235907-B1 | Intermediates useful in making mappicine and related compounds | PHARMACIA & UPJOHN COMPANY | 2001-05-22 | — | — | US | disclosed |
| US-6121451-A | Intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| US-6060600-A | TREATMENT OF AIDS AND OTHER DISEASES CAUSED BY RETROVIRUSES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| US-4029693-A | HYPOTENSIVES, ANTISECRETORY, ANTIFERTILITY | THE UPJOHN COMPANY (US) | 1977-06-14 | — | — | US | disclosed |
| US-4028419-A | PROSTAGLANDINS | THE UPJOIN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4028350-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026909-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4018803-A | 13,14-Didehydro-PG3 compounds | THE UPJOHN COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
| US-4013695-A | PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL | THE UPJOHN COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4001300-A | ANTIULCER, DECONGESTANT, LABOR INDUCER, WOUND HEALER | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3974146-A | Cyanolpoxy intermediates for prostaglandins and process for preparing same | THE UPJOHN COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |