Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18469983 | 0.98 | NPSR1 (0.45) | NPSR1GAAEPHX2TSHRMEN1 | |
| SCHEMBL2276331 | 0.86 | SLC6A4 (0.39) | NPSR1GAAEPHX2 | |
| SCHEMBL2276334 | 0.86 | SLC6A4 (0.39) | NPSR1GAAEPHX2 | |
| SCHEMBL6628285 | 0.84 | L3MBTL1 (0.46) | NPSR1EPHX2TSHRMEN1KMT2A | |
| SCHEMBL24359375 | 0.81 | GAA (0.44) | NPSR1GAATSHRMEN1KMT2A | |
| SCHEMBL8377528 | 0.81 | KMT2A (0.47) | NPSR1GAAEPHX2TSHRMEN1 | |
| SCHEMBL4159697 | 0.79 | EPHX2 (0.40) | NPSR1EPHX2TSHRALDH1A1LMNA | |
| SCHEMBL18494973 | 0.79 | EPHX1 (0.34) | NPSR1GAAEPHX2TSHRALDH1A1 | |
| SCHEMBL18469929 | 0.78 | SMN1; SMN2 (0.37) | GAAMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28933506 | 0.78 | GNAI3 (0.33) | NPSR1GAAEPHX2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |