Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480363 | 0.83 | SLC6A4 (0.44) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8480360 | 0.81 | SLC6A4 (0.43) | ALDH1A1 | |
| SCHEMBL16935877 | 0.80 | PYGL (0.43) | ALDH1A1KDM4EPDE2APDE3BPDE3A | |
| SCHEMBL6628285 | 0.79 | L3MBTL1 (0.46) | EPHX2ALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL7296171 | 0.79 | NPSR1 (0.46) | EPHX2ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL5634109 | 0.79 | — | — | |
| SCHEMBL3525420 | 0.79 | EPHX2 (0.39) | EPHX2ALDH1A1PDE2APDE3BPDE3A | |
| SCHEMBL18469983 | 0.78 | NPSR1 (0.45) | EPHX2ALDH1A1TSHRLMNANPSR1 | |
| SCHEMBL9615293 | 0.78 | ALDH1A1 (0.41) | EPHX2ALDH1A1PDE2APDE3BPDE3A | |
| SCHEMBL2932705 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124820-A1 | C1-Symmetric Bisphospine Ligands and Their Use in the Asymmetric Synthesis of Pregabalin | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
| US-7375241-B2 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | SOLVIAS A.G. (CH) | 2008-05-20 | — | — | US | disclosed |
| EP-1692151-B1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | SOLVIAS AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| EP-1727620-B1 | C1-SYMMETRIC BISPHOSPHINE LIGANDS AND THEIR USE IN THE ASYMMETRIC SYNTHESIS OF PREGABALIN | WARNER LAMBERT CO (US) | 2007-08-29 | — | — | EP | disclosed |
| US-20070142655-A1 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | SOLVIAS AG (CH) | 2007-06-21 | — | — | US | disclosed |
| EP-1692151-A1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | Solvias AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| US-20050228190-A1 | C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin | BAO JIAN | 2005-10-13 | — | — | US | disclosed |
| WO-2005056568-A1 | FERROCENYL-1, 2-DIPHOSPHINES, THE PRODUCTION THEREOF AND THEIR USE | SOLVIAS AG (CH) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142655-A1 | Ferrocenyl-1,2-diphosphines, the production thereof and their use | PHOSPHO1, INPP5B, PPA1 | EPHX2 1156/4885ALDH1A1 2167/4885KDM4E 3839/4885 |
| US-20050228190-A1 | C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin | GABRA5, CNR1, GABRE | EPHX2 1888/4885ALDH1A1 1007/4885KDM4E 2676/4885 |
| US-20090124820-A1 | C1-Symmetric Bisphospine Ligands and Their Use in the Asymmetric Synthesis of Pregabalin | GABRE, GABRP, GABRA5 | EPHX2 1547/4885ALDH1A1 1408/4885KDM4E 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.