Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306648 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7300593 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ADPP4 | |
| SCHEMBL7309254 | 0.77 | PREP (0.59) | LMNAMAPTKMT2AL3MBTL1NPSR1 | |
| SCHEMBL7309249 | 0.77 | PREP (0.59) | LMNAMAPTKMT2AL3MBTL1NPSR1 | |
| SCHEMBL7304770 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL25279026 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28829166 | 0.74 | HSD17B10 (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL30069139 | 0.74 | HSD17B10 (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL23545835 | 0.74 | HSD17B10 (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28606669 | 0.73 | NPC1 (0.55) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |