Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306648 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7296648 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ADPP4DPP8 | |
| SCHEMBL7306680 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ADPP4STS | |
| SCHEMBL8998365 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ADPP4STS | |
| SCHEMBL8998354 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ADPP4STS | |
| SCHEMBL25988648 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASTSL3MBTL1 | |
| SCHEMBL7304770 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7295642 | 0.77 | HDAC8 (0.51) | MEN1KMT2AL3MBTL1KDM4ENPC1 | |
| SCHEMBL7295644 | 0.77 | HDAC8 (0.51) | MEN1KMT2AL3MBTL1KDM4ENPC1 | |
| SCHEMBL23545835 | 0.77 | HSD17B10 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |