Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300593 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL7296648 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL6535959 | 0.83 | KLK7 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL28387244 | 0.83 | KLK7 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL25339275 | 0.83 | KLK7 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL25339274 | 0.83 | KLK7 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL30057132 | 0.83 | KLK7 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL7304770 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL7297691 | 0.81 | KLK7 (0.46) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL18336855 | 0.81 | KLK7 (0.46) | ALDH1A1MEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506256-A | PREVENTION AND/OR TREATMENT OF DEMENTIA, AMNESIA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0468469-A2 | Proline derivatives | Japan Tobacco Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |