Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291318 | 1.00 | PABPC1 (0.33) | PABPC1APOBEC3AAPOBEC3GTDP1FKBP1A | |
| SCHEMBL8943504 | 0.96 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL8943501 | 0.96 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL9133269 | 0.96 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL9135419 | 0.96 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL9135416 | 0.96 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL23670055 | 0.94 | — | — | |
| SCHEMBL31644526 | 0.94 | — | — | |
| SCHEMBL23669704 | 0.94 | — | — | |
| SCHEMBL20946384 | 0.83 | TOP2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583248-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0512343-B1 | Amino acid derivatives and their use as anti-viral agents | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | EP | disclosed |
| US-5430041-A | Amino acid derivatives having antiviral activity | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0512343-A2 | Amino acid derivatives and their use as anti-viral agents | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | disclosed |