SCHEMBL729720

SCHEMBL729720

C=CCC(=CCC=CO)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL462909 0.83 TSHR (0.34) KDM4ETSHR
SCHEMBL462908 0.83 TSHR (0.34) KDM4ETSHR
SCHEMBL731669 0.82 ABAT (0.31)
Propane SCHEMBL15303565 0.78 GRIK1 (0.32) KDM4ETSHR
Butane SCHEMBL10765613 0.76 GRIK1 (0.33) KDM4ETSHR
SCHEMBL87512 0.73
SCHEMBL8982707 0.73
SCHEMBL6024966 0.72 GRIK1 (0.47) KDM4ETSHR
SCHEMBL5133417 0.72 GRIK1 (0.47) KDM4ETSHR
SCHEMBL5133416 0.72 GRIK1 (0.47) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110257289-A1 AB DIBLOCK COPOLYMERS AND APPLICATIONS FOR THEIR USE CHAMELIC LTD (GB) 2011-10-20 US claimed
EP-2342246-A1 AB DIBLOCK COPOLYMERS AND APPLICATIONS FOR THEIR USE Chamelic Ltd (GB) 2011-07-13 EP claimed
EP-0626983-B1 POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS BIOCOMPATIBLES LTD (GB) 1999-04-14 EP claimed
US-8765838-B2 Non-aqueous ink composition for inkjet printing RISO KAGAKU CORPORATION (JP) 2014-07-01 US disclosed
US-8646907-B2 Materials for use in ophthalmic applications and methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-02-11 US disclosed
US-8410190-B2 Wettable hydrogel materials for use in ophthalmic applications and methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2013-04-02 US disclosed
US-20120194779-A1 Materials For Use In Ophthalmic Applications And Methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-08-02 US disclosed
US-20120172486-A1 Wettable Hydrogel Materials For Use In Ophthalmic Applications And Methods COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-07-05 US disclosed
US-20120083567-A1 NON-AQUEOUS INK COMPOSITION FOR INKJET PRINTING RISO KAGAKU CORPORATION (JP) 2012-04-05 US disclosed
US-8136676-B2 a membrane or fibers composed of or coated with methoxyethyl methacrylate/2-/-di(ethylene glycol)ethyl ether methacrylate-2-(diethylamino)ethyl methacrylate terpolymer for the selective removal, reduction or separation of white blood cells and/or platelets from blood by passing blood through the medium UNIVERSITY OF SOUTHAMPTON (GB) 2012-03-20 US disclosed
US-20110257289-A1 AB DIBLOCK COPOLYMERS AND APPLICATIONS FOR THEIR USE CHAMELIC LTD (GB) 2011-10-20 US disclosed
EP-2342246-A1 AB DIBLOCK COPOLYMERS AND APPLICATIONS FOR THEIR USE Chamelic Ltd (GB) 2011-07-13 EP disclosed
WO-2011037893-A2 WETTABLE HYDROGEL MATERIALS FOR USE IN OPHTHALMIC APPLICATIONS AND METHODS COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2011-03-31 WO disclosed
WO-2011037897-A2 MATERIALS FOR USE IN OPHTHALMIC APPLICATIONS AND METHODS COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2011-03-31 WO disclosed
US-20100303890-A1 COPOLYMERS SUITABLE FOR USE IN CORNEAL BANDAGES UNIVERSITY OF SOUTHAMPTON (GB) 2010-12-02 US disclosed
EP-2074155-A2 COPOLYMERS SUITABLE FOR USE IN CORNEAL BANDAGES UNIVERSITY OF SOUTHAMPTON (GB) 2009-07-01 EP disclosed
US-20080190843-A1 Polymers Useful as Medical Materials UNIVERSITY OF SOUTHAMPTON (GB) 2008-08-14 US disclosed
WO-2008047160-A2 COPOLYMERS SUITABLE FOR USE IN CORNEAL BANDAGES UNIVERSITY OF SOUTHAMPTON (GB) 2008-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100303890-A1 COPOLYMERS SUITABLE FOR USE IN CORNEAL BANDAGES CRYAB, CRYAA, UACA KDM4E 2975/4885TSHR 4132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.