Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298398 | 0.83 | GAA (0.39) | GAAPDE3APDE4BHRH3PDE3B | |
| SCHEMBL7287593 | 0.71 | PDE3A (0.42) | GAAPDE3APDE4BHRH3PDE3B | |
| SCHEMBL7296693 | 0.69 | ALDH1A1 (0.39) | GAA | |
| SCHEMBL10389368 | 0.68 | GAA (0.46) | GAAPDE3APDE4BHRH3PDE3B | |
| SCHEMBL10388766 | 0.68 | GAA (0.50) | GAAPDE3APDE4BHRH3PDE3B | |
| SCHEMBL7298799 | 0.66 | CA2 (0.45) | CA2 | |
| SCHEMBL4983802 | 0.65 | GSR (0.51) | GAAPDE3APDE4BHRH3PDE3B | |
| SCHEMBL10341494 | 0.62 | MEN1 (0.60) | HRH3 | |
| SCHEMBL9039217 | 0.62 | HPGD (0.45) | GAACA2 | |
| SCHEMBL9039222 | 0.62 | HPGD (0.45) | GAACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426018-B1 | Thiophene compounds and their pharmaceutical uses | YOSHITIOMI PHARMACEUTICAL IND (JP) | 1997-08-27 | — | — | EP | disclosed |
| EP-0729960-A1 | Thiophene compounds and their use as intermediates in the preparation of antianxiety drugs, hypnotics, antiepileptic drugs and nuotropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5329016-A | Antianxiety, hypnotic agents, antiepileptic agents or nootropics | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5175162-A | Anxiolytic, antiepilepic agents | YOSHITIOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0426018-A2 | Thiophene compounds and their pharmaceutical uses | YOSHITIOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |