Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511944 | 0.73 | CA2 (0.82) | CA2 | |
| SCHEMBL2776823 | 0.72 | TSHR (0.47) | HTTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL13104453 | 0.67 | TSHR (0.42) | KDM4EALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10513879 | 0.67 | ALDH1A1 (0.43) | CA2KDM4EHTTALDH1A1RAB9A | |
| SCHEMBL7586252 | 0.67 | CA2 (0.56) | CA2KDM4EHTTALDH1A1VHL | |
| SCHEMBL9039217 | 0.67 | HPGD (0.45) | CA2HTTTSHR | |
| SCHEMBL9039222 | 0.67 | HPGD (0.45) | CA2HTTTSHR | |
| SCHEMBL20618465 | 0.67 | MEN1 (0.36) | KDM4EHTTALDH1A1TSHRMEN1 | |
| SCHEMBL7297301 | 0.66 | GAA (0.39) | CA2 | |
| SCHEMBL18193400 | 0.64 | KDM4E (0.46) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426018-A2 | Thiophene compounds and their pharmaceutical uses | YOSHITIOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |