SCHEMBL7297540

SCHEMBL7297540

O=C(O)C(Cc1ccccc1)NS(=O)(=O)O

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 9/20 0.65
MMP9 P14780 7/20 0.65
ADAMTS4 O75173 1/20 0.65
ADAMTS5 Q9UNA0 1/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPT P10636 1/20 0.57
POLB P06746 1/20 0.57
MMP1 P03956 1/20 0.57
MMP3 P08254 1/20 0.57
MMP7 P09237 1/20 0.57
MMP13 P45452 1/20 0.57
HTT P42858 1/20 0.53
MME P08473 1/20 0.53
NPSR1 Q6W5P4 1/20 0.51
CA2 P00918 2/20 0.51
CA1 P00915 1/20 0.51
NAALAD2 Q9Y3Q0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7297543 1.00 MMP2 (0.65) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL286031 0.86 MEN1 (0.63) MMP2MMP9ADAMTS4MMECA2
SCHEMBL286032 0.86 MEN1 (0.63) MMP2MMP9ADAMTS4MMECA2
Benzene SCHEMBL28198278 0.84 MMP2 (0.63) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL698062 0.84 MMP2 (0.63) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL698061 0.84 MMP2 (0.63) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL4316657 0.84 MMP2 (0.63) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL4732686 0.84 MMP2 (0.63) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL6436714 0.84 MMP2 (0.63) MMP2MMP9ADAMTS4ADAMTS5ALDH1A1
SCHEMBL6653310 0.83 MMP1 (0.52) MMP2MMP9ADAMTS4MMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119604536-A HER2 binding agents and uses thereof 塞雷乌斯股份有限公司 2025-03-11 CN claimed
CN-118176024-A Reagents for site-specific labelling of proteins with radiohalogen, and methods of making and using the same 杜克大学 2024-06-11 CN claimed
EP-4199968-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF Ambrx, Inc. (US) 2023-06-28 EP claimed
EP-4117732-A1 INTERLEUKIN-2 POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF Ambrx, Inc. (US) 2023-01-18 EP claimed
US-20220226488-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES AMBRX, INC. 2022-07-21 US claimed
WO-2022040596-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2022-02-24 WO claimed
EP-3923991-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES Ambrx, Inc. (US) 2021-12-22 EP claimed
WO-2021183832-A1 INTERLEUKIN-2 POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF AMBRX, INC. (US) 2021-09-16 WO claimed
EP-3844188-A1 ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES Ambrx, Inc. (US) 2021-07-07 EP claimed
CN-112646002-A Sulfoamino acid modified antioxidant oligopeptide and preparation thereof 浙江海洋大学 2021-04-13 CN claimed
WO-2020168017-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES AMBRX, INC. (US) 2020-08-20 WO claimed
WO-2020047176-A1 ANTI-CD3 ANTIBODY FOLATE BIOCONJUGATES AND THEIR USES AMBRX, INC. (US) 2020-03-05 WO claimed
CN-110709106-A Radiolabeled biomolecules and uses thereof 杜克大学 2020-01-17 CN claimed
EP-0443598-B1 Peptides inhibiting the blood coagulation, their process of preparation and their use BEHRINGWERKE AG (DE) 1995-05-17 EP claimed
EP-0443598-A2 Peptides inhibiting the blood coagulation, their process of preparation and their use BEHRINGWERKE Aktiengesellschaft (DE) 1991-08-28 EP claimed
CN-119604536-A HER2 binding agents and uses thereof 塞雷乌斯股份有限公司 2025-03-11 CN disclosed
CN-118176024-A Reagents for site-specific labelling of proteins with radiohalogen, and methods of making and using the same 杜克大学 2024-06-11 CN disclosed
EP-0739338-A1 NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE THE WICHITA STATE UNIVERSITY (US) 1996-10-30 EP disclosed
US-5550139-A ANTIINFLAMMATORY AGENT, ANTITUMOR AGENT, ANTICARCINOGENIC AGENT THE WICHITA STATE UNIVERSITY (US) 1996-08-27 US disclosed
WO-1995018797-A1 NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE THE WICHITA STATE UNIVERSITY (US) 1995-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220226488-A1 COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES TLR1, TLR3, TLR2 MMP2 3843/4885MMP9 3957/4885ADAMTS4 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.