Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464672 | 0.87 | DPP8 (0.69) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL453671 | 0.87 | DPP8 (0.69) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL5816135 | 0.87 | DPP8 (0.69) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL25815858 | 0.86 | TGM2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4DPP8 | |
| SCHEMBL22184125 | 0.86 | TGM2 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4DPP8 | |
| Hydrochloric Acid SCHEMBL7297967 | 0.86 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL21219282 | 0.86 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL7028548 | 0.86 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL7025382 | 0.86 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| Hydrochloric Acid SCHEMBL18770783 | 0.86 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244836-A2 | Tripeptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-11 | — | — | EP | disclosed |