SCHEMBL729777

SCHEMBL729777

[CH2]/C=C/c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 1/20 0.58
▸ NFKB1 P19838 3/20 0.56
▸ CDK4 P11802 1/20 0.56
▸ CCND1 P24385 1/20 0.56
▸ JUN P05412 1/20 0.56
▸ NFE2L2 Q16236 1/20 0.56
▸ CA2 P00918 6/20 0.54
▸ CA4 P22748 2/20 0.54
▸ CA1 P00915 1/20 0.54
▸ TRIM24 O15164 1/20 0.52
▸ TRIM33 Q9UPN9 1/20 0.52
▸ MAPT P10636 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ BCHE P06276 1/20 0.48
▸ GUSB P08236 1/20 0.48
▸ CA12 O43570 5/20 0.45
▸ CA9 Q16790 3/20 0.45
▸ KDM4E B2RXH2 2/20 0.45
▸ SIRT2 Q8IXJ6 1/20 0.45
▸ ECE2 P0DPD6 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1767263 1.00 TRPA1 (0.58) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL717976 0.84 TRPA1 (0.76) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL108389 0.84 TRPA1 (0.76) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL29149776 0.81 ERN1 (0.56) CA2CA1MAPTLMNAKDM4E
SCHEMBL28398848 0.77 TRPA1 (0.60) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL3190851 0.77 TRPA1 (0.60) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL6154323 0.77 TRPA1 (0.60) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL19970163 0.76 CDK4 (0.63) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL1876846 0.75 TRPA1 (0.58) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL7949288 0.75 TRPA1 (0.58) TRPA1NFKB1CDK4CCND1JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993801-B2 Base-modified nucleotides as substrates for TdT-based enzymatic nucleic acid synthesis ILLUMINA SINGAPORE PTE. LTD. (SG) 2024-05-28 — — US claimed
EP-4185707-A1 BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID Illumina Singapore Pte Ltd (SG) 2023-05-31 — — EP claimed
CN-114657238-A Medlar 40K liquid phase chip and application 宁夏农林科学院枸杞科学研究所 2022-06-24 — — CN claimed
US-20220025421-A1 BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID SYNTHESIS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-01-27 — — US claimed
US-10364313-B2 Method for producing an ablative resin ARIANEGROUP SAS (FR) 2019-07-30 — — US claimed
EP-3247730-B1 METHOD FOR PRODUCING AN ABLATIVE RESIN ARIANEGROUP SAS (FR) 2019-07-03 — — EP claimed
EP-3247636-B1 METHOD FOR PRODUCING AN ABLATIVE RESIN ARIANEGROUP SAS (FR) 2019-06-12 — — EP claimed
US-10246544-B2 Method for producing an ablative resin ARIANEGROUP SAS (FR) 2019-04-02 — — US claimed
US-20180022853-A1 METHOD FOR PRODUCING AN ABLATIVE RESIN ARIANEGROUP SAS (FR) 2018-01-25 — — US claimed
US-20180009928-A1 METHOD FOR PRODUCING AN ABLATIVE RESIN CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-01-11 — — US claimed
US-9023471-B2 Lignin-based nanostructures UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2015-05-05 — — US claimed
US-20140050924-A1 LIGNIN-BASED NANOSTRUCTURES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2014-02-20 — — US claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 — — US claimed
US-20040229812-A1 Mimetic insect allatostatin analogs for insect control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2004-11-18 — — US claimed
US-20040039159-A1 Mimetic insect allatostatin analogs for insect control NACHMAN RONALD J (US) 2004-02-26 — — US claimed
US-20030161857-A1 Mimetic insect allatostatin analogs for insect control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2003-08-28 — — US claimed
US-6207643-B1 PSEUDOPEPTIDE ANALOGS ARE PRODUCED WHICH EXHIBIT AN OVERALL AMPHIPHILIC NATURE AND WHICH ARE CAPABLE OF PENETRATING THE INSECT CUTICLE WHILE STILL RETAINING BIOLOGICAL ACTIVITY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2001-03-27 — — US claimed
EP-0370492-B1 INDOLE-ALDEHYDE HAIR DYES Bristol-Myers Squibb Company (US) 1993-01-27 — — EP claimed
US-4932977-A Indole-aldehyde hair dyes CLAIROL INCORPORATED (US) 1990-06-12 — — US claimed
EP-0370492-A1 Indole-aldehyde hair dyes Bristol-Myers Squibb Company (US) 1990-05-30 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039159-A1 Mimetic insect allatostatin analogs for insect control ANPEP, CTRL, DNPEP TRPA1 1972/4885NFKB1 4099/4885CDK4 4627/4885
US-20030161857-A1 Mimetic insect allatostatin analogs for insect control ANPEP, CTRL, DNPEP TRPA1 1972/4885NFKB1 4099/4885CDK4 4627/4885
US-20040229812-A1 Mimetic insect allatostatin analogs for insect control ANPEP, CTRL, DNPEP TRPA1 1972/4885NFKB1 4099/4885CDK4 4627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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