Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | CCND1 | P24385 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729777 | 1.00 | TRPA1 (0.58) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL717976 | 0.84 | TRPA1 (0.76) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL108389 | 0.84 | TRPA1 (0.76) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL29149776 | 0.81 | ERN1 (0.56) | CA2CA1MAPTLMNAKDM4E | |
| SCHEMBL28398848 | 0.77 | TRPA1 (0.60) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL3190851 | 0.77 | TRPA1 (0.60) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL6154323 | 0.77 | TRPA1 (0.60) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL19970163 | 0.76 | CDK4 (0.63) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL1876846 | 0.75 | TRPA1 (0.58) | TRPA1NFKB1CDK4CCND1JUN | |
| SCHEMBL7949288 | 0.75 | TRPA1 (0.58) | TRPA1NFKB1CDK4CCND1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993801-B2 | Base-modified nucleotides as substrates for TdT-based enzymatic nucleic acid synthesis | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2024-05-28 | — | — | US | claimed |
| EP-4185707-A1 | BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID | Illumina Singapore Pte Ltd (SG) | 2023-05-31 | — | — | EP | claimed |
| US-20230119068-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | OHIO STATE INNOVATION FOUNDATION | 2023-04-20 | — | — | US | claimed |
| US-20220025421-A1 | BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID SYNTHESIS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-01-27 | — | — | US | claimed |
| WO-2021163679-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | OHIO STATE INNOVATION FOUNDATION (US) | 2021-08-19 | — | — | WO | claimed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | claimed |
| US-20100056616-A1 | IEJIMALID ANALOGA AND USES THEREOF | STUDIENGESELLSCHAFT KOHLE MBH | 2010-03-04 | — | — | US | claimed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | claimed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | claimed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | claimed |
| US-20240200059-A1 | PHOTOCLEAVABLE GUIDE RNAS AND METHODS OF USE THEREOF | VOR BIOPHARMA INC. (US) | 2024-06-20 | — | — | US | disclosed |
| US-11993801-B2 | Base-modified nucleotides as substrates for TdT-based enzymatic nucleic acid synthesis | ILLUMINA SINGAPORE PTE. LTD. (SG) | 2024-05-28 | — | — | US | disclosed |
| US-20240159706-A1 | MALDI-MS METHOD, PHOTO-SENSITIVE MALDI MATRIX COMPOSITE AND PHOTO-CAGED MALDI MATRIX COMPOUND FOR USE IN SAID METHOD AND RESPECTIVE USES | SIRIUS FINE CHEMICALS SICHEM GMBH (DE) | 2024-05-16 | — | — | US | disclosed |
| US-11982880-B2 | Accommodating cavity lens shaped with photocleavable insert | ONEFOCUS VISION, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-11984317-B2 | EUV patterning methods, structures, and materials | INTEL CORPORATION (US) | 2024-05-14 | — | — | US | disclosed |
| EP-1475632-A1 | METHOD OF ANALYZING AMINOFUNCTIONAL COMPOUND AND ANALYTICAL REAGENT | Ajinomoto Co., Inc. (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20030129504-A1 | Photosensitive resin compositon, transfer material, image forming method, color filter and producing method thereof and photomask and producing method thereof | FUJI PHOTO FILM CO., LTD. | 2003-07-10 | — | — | US | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | TRPA1 3038/4885NFKB1 1554/4885CDK4 1103/4885 |
| US-20230119068-A1 | METHODS FOR RAPID SYNTHESIS OF PYRANOANTHOCYANINS | HCCS, PPOX, RNGTT | TRPA1 3912/4885NFKB1 3807/4885CDK4 2498/4885 |
| US-20100056616-A1 | IEJIMALID ANALOGA AND USES THEREOF | CCND1, CCND2, DPYD | TRPA1 4844/4885NFKB1 1675/4885CDK4 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.