Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | IAPP | P10997 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308223 | 0.85 | ERN1 (0.65) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL729777 | 0.81 | TRPA1 (0.58) | POLBRAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL1767263 | 0.81 | TRPA1 (0.58) | POLBRAB9AALDH1A1HPGDALOX15 | |
| SCHEMBL21684 | 0.79 | TRPA1 (0.61) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL3237524 | 0.77 | ERN1 (0.56) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL9251009 | 0.77 | IAPP (0.60) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL9251021 | 0.77 | IAPP (0.60) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL9745412 | 0.77 | IAPP (0.60) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL29356117 | 0.76 | ERN1 (0.60) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL131222 | 0.76 | ERN1 (0.60) | ERN1IAPPPOLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |