Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491360 | 0.79 | CAPN1 (0.53) | KMT2AMEN1CAPN1LMNACYP2C19 | |
| SCHEMBL6504201 | 0.78 | SMN1; SMN2 (0.65) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL7307342 | 0.78 | SMN1; SMN2 (0.56) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9083440 | 0.76 | CTSK (0.57) | CAPN1 | |
| SCHEMBL7288757 | 0.76 | CTSK (0.57) | CAPN1 | |
| SCHEMBL7413026 | 0.76 | CTSK (0.57) | CAPN1 | |
| SCHEMBL7303296 | 0.76 | ALDH1A1 (0.59) | CAPN1LMNATDP1ALDH1A1 | |
| SCHEMBL7304202 | 0.76 | ALDH1A1 (0.59) | CAPN1LMNATDP1ALDH1A1 | |
| SCHEMBL7301256 | 0.76 | SMN1; SMN2 (0.56) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL7310952 | 0.75 | SMN1; SMN2 (0.61) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |