Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.57 |
| ▸ | CTSB | P07858 | 7/20 | 0.57 |
| ▸ | CTSL | P07711 | 3/20 | 0.57 |
| ▸ | CTSH | P09668 | 2/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083440 | 1.00 | CTSK (0.57) | CTSKCTSBCTSLCTSHCAPN1 | |
| SCHEMBL7413026 | 1.00 | CTSK (0.57) | CTSKCTSBCTSLCTSHCAPN1 | |
| SCHEMBL7800081 | 0.87 | MMP8 (0.49) | CTSKCTSBCTSLCTSH | |
| SCHEMBL3132344 | 0.87 | CTSB (0.66) | CTSBCTSLCAPN1 | |
| SCHEMBL630290 | 0.87 | CTSB (0.66) | CTSBCTSLCAPN1 | |
| SCHEMBL3337955 | 0.87 | CTSB (0.66) | CTSBCTSLCAPN1 | |
| SCHEMBL24534164 | 0.86 | CTSK (0.58) | CTSKCTSBCTSLCTSHCAPN1 | |
| SCHEMBL8918730 | 0.86 | CTSK (0.58) | CTSKCTSBCTSLCTSHCAPN1 | |
| SCHEMBL28134652 | 0.86 | CTSK (0.58) | CTSKCTSBCTSLCTSHCAPN1 | |
| SCHEMBL7296186 | 0.86 | CTSK (0.72) | CTSKCTSBCTSLCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |