SCHEMBL729807

SCHEMBL729807

CCO[SiH](OCC)OCCCNC(N)=O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TSHR P16473 2/20 0.36
ACHE P22303 8/20 0.35
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728061 0.95 CA12 (0.40) CA12CA1CA2CA9TSHR
SCHEMBL728059 0.93 ACHE (0.39) CA12CA1CA2CA9ACHE
SCHEMBL728338 0.89 ALOX15 (0.32) CA12CA1CA2CA9
SCHEMBL13720551 0.83 MMP1 (0.36) ACHEALDH1A1MEN1KMT2A
SCHEMBL20724724 0.77 TSHR (0.56) TSHRHPGDHTTNPC1RAB9A
SCHEMBL432323 0.76 CA12 (0.34) CA12CA1CA2CA9TSHR
SCHEMBL483443 0.75 CA12 (0.37) CA12CA1CA2CA9ACHE
SCHEMBL28907172 0.75 CA12 (0.33) CA12CA1CA2CA9TSHR
SCHEMBL23631709 0.73 CA12 (0.37) CA12CA1CA2CA9TSHR
Urea SCHEMBL9068285 0.73 ALOX15 (0.46) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed