Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SERPINH1 | P50454 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112006 | 0.78 | TSHR (0.44) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL9601062 | 0.78 | ALDH1A1 (0.44) | MAPK1ALDH1A1TDP1MAPTHTT | |
| SCHEMBL11309197 | 0.77 | MAPK1 (0.42) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL7297677 | 0.76 | MAPK1 (0.46) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL19301482 | 0.73 | CYP3A4 (0.39) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL14123914 | 0.72 | SMN1; SMN2 (0.39) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL12112007 | 0.71 | TSHR (0.41) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL12112004 | 0.70 | MAPK1 (0.50) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL2939873 | 0.70 | MAPK1 (0.50) | MAPK1TSHRCYP3A4ALDH1A1TDP1 | |
| SCHEMBL14254642 | 0.70 | LMNA (0.49) | MAPK1TSHRCYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |