Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.59 |
| ▸ | GAA | P10253 | 13/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18830754 | 0.84 | MAPT (0.65) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL8465011 | 0.80 | MAPT (0.66) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL8693690 | 0.80 | MAPT (0.63) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL656253 | 0.80 | GAA (0.69) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL5084625 | 0.79 | MAPT (0.67) | MAPTGAAKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9796928 | 0.78 | MAPT (0.61) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL5080900 | 0.77 | MAPT (0.64) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL8550702 | 0.77 | GAA (0.59) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL1336716 | 0.77 | MAPT (0.62) | MAPTGAAKDM4EALDH1A1MEN1 | |
| SCHEMBL952942 | 0.77 | MAPT (0.59) | MAPTGAAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604353-B1 | Benzimidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1998-07-01 | — | — | EP | disclosed |