SCHEMBL952942

SCHEMBL952942

Nc1cc(Br)ccc1Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.59
GAA P10253 10/20 0.59
KDM4E B2RXH2 9/20 0.59
ALDH1A1 P00352 8/20 0.59
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
LMNA P02545 5/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
CYP2D6 P10635 1/20 0.59
GFER P55789 4/20 0.57
HPGD P15428 4/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
HSD17B10 Q99714 2/20 0.57
THRB P10828 1/20 0.57
SMN1; SMN2 Q16637 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
HTT P42858 3/20 0.50
ALOX15 P16050 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23652487 0.95 GAA (0.58) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL12946054 0.88 MAPK13 (0.47) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL1519245 0.85 MAPT (0.59) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL9950077 0.84 GAA (0.52) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL11468680 0.81 KDM4E (0.56) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL29548950 0.81 MAPK14 (0.43) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL3013794 0.81 MAPK14 (0.43) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL11400584 0.81 MAPK13 (0.49) MAPTGAAKDM4EALDH1A1MEN1
SCHEMBL16239045 0.81 KEAP1 (0.55) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL23652372 0.80 MAPT (0.58) MAPTGAAKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111224002-B Organometallic compound and organic light emitting device including the same 三星显示有限公司 2024-11-26 CN disclosed
US-11665961-B2 Heterocyclic compound and organic light emitting device using same LT MATERIALS CO., LTD. (KR) 2023-05-30 US disclosed
US-20230120308-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2023-04-20 US disclosed
EP-4124619-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND Idemitsu Kosan Co., Ltd. (JP) 2023-02-01 EP disclosed
CN-111224002-A Organometallic compound and organic light emitting device including the same 三星显示有限公司 2020-06-02 CN disclosed
US-20200168816-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-28 US disclosed
WO-2019078636-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 희성소재(주) 2019-04-25 WO disclosed
EP-3053985-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LG CHEMICAL LTD (KR) 2018-10-31 EP disclosed
US-10032997-B2 Heterocyclic compound and organic light-emitting element using same LG CHEM, LTD. (KR) 2018-07-24 US disclosed
US-20180123053-A1 BIPOLAR MATERIALS AND ORGANIC LIGHT EMITTING DIODES YUAN ZE UNIVERSITY (TW) 2018-05-03 US disclosed
WO-2008073459-A1 ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-06-19 WO disclosed
US-20070280928-A1 Combined treatment with an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors OSI PHARMACEUTICALS, INC. 2007-12-06 US disclosed
US-20070280928-A1 Combined treatment with an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors OSI PHARMACEUTICALS, INC. 2007-12-06 US disclosed
US-20070280928-A1 Combined treatment with an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors OSI PHARMACEUTICALS, INC. 2007-12-06 US disclosed
WO-2007106503-A2 COMBINED TREATMENT WITH AN EGFR KINASE INHIBITOR AND AN AGENT THAT SENSITIZES TUMOR CELLS TO THE EFFECTS OF EGFR KINASE INHIBITORS OSI PHARMACEUTICALS, INC. (US) 2007-09-20 WO disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20070112005-A1 mammalian Target Of Rapamycin (mTOR) kinase; for treatment of lymphoma or ovarian cancer OSI PHARMACEUTICALS, INC. 2007-05-17 US disclosed
US-20070112005-A1 mammalian Target Of Rapamycin (mTOR) kinase; for treatment of lymphoma or ovarian cancer OSI PHARMACEUTICALS, INC. 2007-05-17 US disclosed
US-20070112005-A1 mammalian Target Of Rapamycin (mTOR) kinase; for treatment of lymphoma or ovarian cancer OSI PHARMACEUTICALS, INC. 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230120308-A1 COMPOUND, MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND ODC1, OR10J3, PIEZO1 MAPT 1600/4885GAA 1046/4885KDM4E 1561/4885
US-10032997-B2 Heterocyclic compound and organic light-emitting element using same CRY1, CRY2, NR2E3 MAPT 1252/4885GAA 1696/4885KDM4E 1127/4885
US-20180123053-A1 BIPOLAR MATERIALS AND ORGANIC LIGHT EMITTING DIODES MAP1LC3A, MAP1LC3B, MAP1LC3C MAPT 106/4885GAA 3109/4885KDM4E 3086/4885
US-20070280928-A1 Combined treatment with an EGFR kinase inhibitor and an agent that sensitizes tumor cells to the effects of EGFR kinase inhibitors EGFR, ERBB2, RICTOR MAPT 1654/4885GAA 1689/4885KDM4E 3387/4885
US-20070112005-A1 mammalian Target Of Rapamycin (mTOR) kinase; for treatment of lymphoma or ovarian cancer MTOR, MAPKAP1, RPS6KA1 MAPT 3825/4885GAA 2198/4885KDM4E 1473/4885
US-11665961-B2 Heterocyclic compound and organic light emitting device using same CRY1, CYP1B1, CRY2 MAPT 2733/4885GAA 3322/4885KDM4E 3112/4885
US-20200168816-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CHRM1, L1CAM, L3MBTL1 MAPT 1510/4885GAA 3950/4885KDM4E 1577/4885
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EHD1, HCN2, ODC1 MAPT 3456/4885GAA 4277/4885KDM4E 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.