SCHEMBL656253

SCHEMBL656253

Nc1ccc(Nc2ccccc2)c(N)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 12/20 0.69
ALDH1A1 P00352 8/20 0.69
TDP1 Q9NUW8 5/20 0.69
HTT P42858 3/20 0.69
ALOX15 P16050 2/20 0.69
MAPT P10636 13/20 0.63
KDM4E B2RXH2 11/20 0.63
MEN1 O00255 6/20 0.63
KMT2A Q03164 6/20 0.63
LMNA P02545 3/20 0.63
CYP1A2 P05177 2/20 0.63
CYP2C9 P11712 2/20 0.63
CYP2C19 P33261 2/20 0.63
CYP2D6 P10635 1/20 0.63
L3MBTL1 Q9Y468 4/20 0.61
GFER P55789 4/20 0.61
HPGD P15428 4/20 0.61
HSD17B10 Q99714 4/20 0.61
THRB P10828 2/20 0.61
SMN1; SMN2 Q16637 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11794649 0.89 MAPT (0.56) GAAALDH1A1TDP1HTTALOX15
SCHEMBL10531579 0.87 MAPT (0.63) GAAALDH1A1TDP1HTTALOX15
SCHEMBL11804940 0.85 MAPT (0.56) GAAALDH1A1TDP1HTTALOX15
SCHEMBL11795177 0.84 MAOA (0.53) GAAALDH1A1TDP1HTTALOX15
Hydrochloric Acid SCHEMBL2641979 0.84 GAA (0.51) GAAALDH1A1TDP1HTTALOX15
SCHEMBL8465011 0.83 MAPT (0.66) GAAALDH1A1TDP1HTTALOX15
SCHEMBL8693690 0.83 MAPT (0.63) GAAALDH1A1TDP1HTTALOX15
SCHEMBL3425246 0.83 GAA (0.63) GAAALDH1A1TDP1HTTALOX15
SCHEMBL5084625 0.82 MAPT (0.67) GAAALDH1A1TDP1HTTALOX15
SCHEMBL11798862 0.82 MAPK13 (0.72) GAAALDH1A1TDP1HTTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079787-A Preparation method of p-phenylenediamine anti-aging agent intermediate 2, 4-diaminodiphenylamine 2026-05-26 CN claimed
CN-119241371-A P-phenylenediamine compound and preparation method and application thereof 山东阳谷华泰化工股份有限公司 2025-01-03 CN claimed
CN-117702527-B Preparation method and application of high-permeability carbon paper for fuel cell 湖南隆深氢能科技有限公司 2024-12-06 CN claimed
CN-117511006-B Rubber shock pad and preparation process thereof 云南国为机械科技有限公司 2024-08-23 CN claimed
CN-118006126-A Liquid crystal polyamide-imide alloy material and preparation method thereof 中国科学技术大学 2024-05-10 CN claimed
CN-117702527-A Preparation method and application of high-permeability carbon paper for fuel cell 湖南隆深氢能科技有限公司 2024-03-15 CN claimed
CN-117511006-A Rubber shock pad and preparation process thereof 云南国为机械科技有限公司 2024-02-06 CN claimed
CN-111971119-B Heterogeneous catalyst for carbamate synthesis 科思创知识产权两合公司 2023-12-08 CN claimed
CN-117089943-A Single-walled carbon nanotube reinforced heterocyclic aramid fiber and preparation method thereof 北京石墨烯研究院 2023-11-21 CN claimed
CN-114768545-B Nitrocellulose microporous membrane and continuous preparation method thereof 青岛吉景新型材料有限公司 2023-11-10 CN claimed
CN-1594463-A Light catalyzed oxidation reduction degradation decolorization writing ink used for blackboard and degradation promoter thereof LIN JINDONG (CN) 2005-03-16 CN claimed
US-20030165559-A1 Non-absorbent articles containing additives KIMBERLY-CLARK WORLDWIDE, INC. 2003-09-04 US claimed
US-20030158156-A1 Methods for inhibiting the production of TSST-1 KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
US-20030157149-A1 Menstrual tampons comprising cerulenin, triclosan, or hexachlorophene to inhibit production of toxic shock syndrome toxins by gram-positive bacteria KIMBERLY-CLARK WORLDWIDE, INC. 2003-08-21 US claimed
CN-1023116-C Method for purifying methacrylic acid MITSUI TOATSU CHEMICALS (JP) 1993-12-15 CN claimed
US-5196578-A Distillation with specific amines MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-03-23 US claimed
EP-0312191-B1 PROCESS FOR PURIFYING METHACRYLIC ACID MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-16 EP claimed
US-4995997-A Containing aromatic amine YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) 1991-02-26 US claimed
EP-0388320-A1 Antibacterial water-soluble cutting fluids resistant to yeast-like fungi YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) 1990-09-19 EP claimed
EP-0312191-A2 Process for purifying methacrylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030158156-A1 Methods for inhibiting the production of TSST-1 TST, TSSK1B, DNTT GAA 1623/4885ALDH1A1 3495/4885TDP1 1529/4885
US-20030165559-A1 Non-absorbent articles containing additives CNOT1, DCUN1D1, CNDP2 GAA 901/4885ALDH1A1 3289/4885TDP1 1263/4885
US-20030157149-A1 Menstrual tampons comprising cerulenin, triclosan, or hexachlorophene to inhibit production of toxic shock syndrome toxins by gram-positive bacteria TPSAB1, TPT1, TST GAA 2844/4885ALDH1A1 3909/4885TDP1 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.