SCHEMBL729895

SCHEMBL729895

COC(CCCCCCCNC(N)=O)(OC)O[SiH3]

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
HIF1A Q16665 1/20 0.35
PAOX Q6QHF9 2/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
TACR3 P29371 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728331 0.98 EPHX1 (0.34) EPHX1TDP1MAOAMAOBKDM4E
SCHEMBL728044 0.95 TDP1 (0.31) EPHX1TDP1MAOAMAOB
SCHEMBL728595 0.88
SCHEMBL28369762 0.79 CA12 (0.31)
SCHEMBL729894 0.78 EPHX1 (0.35) EPHX1TDP1MAOAMAOBKDM4E
SCHEMBL1069336 0.77 MAOA (0.38) EPHX1TDP1MAOAMAOBKDM4E
SCHEMBL29123317 0.77 TSHR (0.38)
SCHEMBL28309517 0.76 TSHR (0.33) TDP1
SCHEMBL29091821 0.76 CA12 (0.37) EPHX1MAOAMAOBKDM4EMAPK1
SCHEMBL432321 0.74 MAOA (0.35) TDP1MAOAMAOBKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed