SCHEMBL728331

SCHEMBL728331

COC(CCCCNC(N)=O)(OC)O[SiH3]

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
PAOX Q6QHF9 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
POLB P06746 2/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729895 0.98 EPHX1 (0.37) EPHX1TDP1MAOAMAOBKDM4E
SCHEMBL728044 0.97 TDP1 (0.31) EPHX1TDP1MAOAMAOBTSHR
SCHEMBL728595 0.89
SCHEMBL28369762 0.80 CA12 (0.31)
SCHEMBL1069336 0.79 MAOA (0.38) EPHX1TDP1MAOAMAOBKDM4E
SCHEMBL29123317 0.78 TSHR (0.38) ALDH1A1SMN1; SMN2TSHR
SCHEMBL28309517 0.77 TSHR (0.33) TDP1TSHR
SCHEMBL29091821 0.77 CA12 (0.37) EPHX1MAOAMAOBKDM4EMAPK1
SCHEMBL729894 0.76 EPHX1 (0.35) EPHX1TDP1MAOAMAOBKDM4E
SCHEMBL432321 0.75 MAOA (0.35) TDP1MAOAMAOBKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11066750-B2 Metal corrosion inhibition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-07-20 US claimed
CN-107573846-B Coating composition and method for determining uniformity and thickness of silane pretreatment 莫门蒂夫性能材料股份有限公司 2021-03-12 CN claimed
US-9976218-B2 Conversion coating composition comprising a dye and a method for coating a metal surface with said conversion coating composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-05-22 US claimed
US-20170240750-A1 COATING COMPOSITION AND METHOD FOR DETERMINING THE UNIFORMITY AND THICKNESS OF A NO-RINSE SILANE PRETREATMENT MOMENTIVE PERFORMANCE MATERIALS INC. 2017-08-24 US claimed
US-9676948-B2 Coating composition and method for determining the uniformity and thickness of a no-rinse silane pretreatment MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-06-13 US claimed
EP-2978816-A1 COATING COMPOSITION AND METHOD FOR DETERMINING THE UNIFORMITY AND THICKNESS OF A NO-RINSE SILANE PRETREATMENT Momentive Performance Materials Inc. (US) 2016-02-03 EP claimed
EP-2191042-B1 METAL CORROSION INHIBITION MOMENTIVE PERFORMANCE MAT INC (US) 2015-07-22 EP claimed
US-20140342164-A1 COATING COMPOSITION AND METHOD FOR DETERMINING THE UNIFORMITY AND THICKNESS OF A NO-RINSE SILANE PRETREATMENT MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-11-20 US claimed
WO-2014160637-A1 COATING COMPOSITION AND METHOD FOR DETERMINING THE UNIFORMITY AND THICKNESS OF A NO-RINSE SILANE PRETREATMENT MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-10-02 WO claimed
US-8609755-B2 Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane MOMENTIVE PERFOMANCE MATERIALS INC. (US) 2013-12-17 US claimed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP claimed
US-20110033719-A1 METAL CORROSION INHIBITION MOMENTIVE PERFORMANCE MATERIALS INC. 2011-02-10 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO claimed
US-20100178521-A1 SILANE COATING COMPOSITIONS CONTAINING SILICON-BASED POLYETHER COPOLYMERS, METHODS FOR COATING METAL SURFACES AND ARTICLESMADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-07-15 US claimed
EP-2191042-A1 METAL CORROSION INHIBITION Momentive Performance Materials Nc. (US) 2010-06-02 EP claimed
EP-2099953-A2 STORAGE STABLE COMPOSITION OF PARTIAL AND/OR COMPLETE CONDENSATE OF HYDROLYZABLE ORGANOFUNCTIONAL SILANE Momentive Performance Materials Inc. (US) 2009-09-16 EP claimed
WO-2009029243-A1 METAL CORROSION INHIBITION MOMENTIVE PERFORMANCE MATERIALS NC. (US) 2009-03-05 WO claimed
WO-2008041976-A2 STORAGE STABLE COMPOSITION OF PARTIAL AND/OR COMPLETE CONDENSATE OF HYDROLYZABLE ORGANOFUNCTIONAL SILANE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-04-10 WO claimed
US-20070090329-A1 Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane MOMENTIVE PERFORMANCE MATERIALS INC. 2007-04-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110033719-A1 METAL CORROSION INHIBITION SLC14A1, SEM1, UFM1 EPHX1 4295/4885TDP1 4618/4885MAOA 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.