SCHEMBL729894

SCHEMBL729894

COC(CCCCCCNC(N)=O)(CO[SiH3])OC

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
PAOX Q6QHF9 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728330 0.95
SCHEMBL728043 0.89
SCHEMBL728594 0.78
SCHEMBL729895 0.78 EPHX1 (0.37) EPHX1MAOAMAOBKDM4EMAPK1
SCHEMBL728331 0.76 EPHX1 (0.34) EPHX1MAOAMAOBKDM4EMAPK1
SCHEMBL728044 0.72 TDP1 (0.31) EPHX1MAOAMAOBTDP1
SCHEMBL1770490 0.72 KDM4E (0.38) EPHX1MAOAMAOBKDM4EMAPK1
SCHEMBL1069336 0.71 MAOA (0.38) EPHX1MAOAMAOBKDM4EMAPK1
SCHEMBL11173620 0.71 KDM4E (0.52) EPHX1KDM4EMAPK1HIF1APAOX
SCHEMBL1309360 0.71 KDM4E (0.52) EPHX1KDM4EMAPK1HIF1APAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed