Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482642 | 0.87 | ABCC9 (0.44) | ABCC9IDO1TRPV1 | |
| SCHEMBL7253544 | 0.77 | IDO1 (0.44) | IDO1 | |
| SCHEMBL13380562 | 0.77 | IDO1 (0.44) | IDO1 | |
| SCHEMBL7258587 | 0.70 | KCNE1 (0.38) | ABCC9IDO1 | |
| SCHEMBL2878172 | 0.70 | PDGFRB (0.39) | IDO1 | |
| SCHEMBL2878170 | 0.70 | PDGFRB (0.39) | IDO1 | |
| SCHEMBL10424910 | 0.69 | IDO1 (0.35) | IDO1 | |
| SCHEMBL7288370 | 0.68 | IDO1 (0.36) | IDO1 | |
| SCHEMBL6274078 | 0.68 | IDO1 (0.40) | IDO1 | |
| SCHEMBL5868357 | 0.68 | IDO1 (0.40) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0308792-A2 | Azachromane derivatives | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |