Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | DRD4 | P21917 | 5/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29831643 | 1.00 | HTR1A (0.62) | HTR1ADRD2DRD4DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29832024 | 0.98 | HTR1A (0.61) | HTR1ADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL2113305 | 0.84 | HTR1A (0.76) | HTR1ADRD2DRD4DRD3KDM4E | |
| SCHEMBL11104836 | 0.83 | ALDH1A1 (0.47) | HTR1ADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL3436276 | 0.82 | ATM (0.56) | ALDH1A1HTR7GAALMNAAKR1C3 | |
| Hydrochloric Acid SCHEMBL1374032 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EGAAGFERLMNA | |
| SCHEMBL3664190 | 0.80 | DRD2 (0.59) | HTR1ADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL24495626 | 0.79 | ALDH1A1 (0.55) | HTR1ADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL28360934 | 0.79 | ALDH1A1 (0.55) | HTR1ADRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL6301694 | 0.79 | MAPT (0.72) | HTR1ADRD4ALDH1A1HTR7GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118966-A1 | AGENT FOR PROMOTING NUCLEIC ACID MOLECULE UPTAKE INTO CELLS, PHARMACEUTICAL COMPOSITION, AND NOVEL COMPOUND | 国立大学法人京都大学 | 2022-06-09 | — | — | WO | disclosed |
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |