Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.50 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123023 | 0.84 | GPR84 (0.55) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL13806393 | 0.84 | GPR84 (0.55) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL436143 | 0.78 | ALDH1A1 (0.52) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL1421538 | 0.77 | ALDH1A1 (0.50) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL2747859 | 0.77 | HTT (0.53) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL22734301 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL15045828 | 0.76 | GPR84 (0.61) | KDM4EALDH1A1IMPDH2CCNE2CDK4 | |
| SCHEMBL10341064 | 0.75 | KDM4E (0.71) | KDM4EALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL30542063 | 0.75 | KDM4E (0.71) | KDM4EALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL10631604 | 0.75 | CA2 (0.50) | KDM4EALDH1A1IMPDH2CCNE2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013061-A1 | 4(1H)QUINOLONE DERIVATIVES | LABORATORIOS ALMIRALL, SA (ES) | 1991-09-05 | — | — | WO | disclosed |
| EP-0445062-A1 | 4(1H)Quinolone derivatives | LABORATORIOS ALMIRALL SA (ES) | 1991-09-04 | — | — | EP | disclosed |