Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291428 | 0.81 | HPGD (0.50) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7296614 | 0.78 | ALDH1A1 (0.47) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7291292 | 0.76 | AR (0.40) | KMT2AMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL6183437 | 0.71 | CA12 (0.58) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10717542 | 0.70 | ALDH1A1 (0.62) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10743471 | 0.69 | LMNA (0.51) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4707412 | 0.69 | RXFP1 (0.50) | HPGDKMT2AMAPTLMNABTK | |
| SCHEMBL27806654 | 0.68 | CES2 (0.52) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL22195276 | 0.67 | KMT2A (0.36) | HPGDKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL31444308 | 0.66 | KCNA5 (0.51) | KMT2AALDH1A1LMNABTKTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | claimed |
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |