Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490928 | 0.77 | TSHR (0.38) | FDPSSMPD1TSHRTHRBGGPS1 | |
| Heptane SCHEMBL11155553 | 0.75 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL28424130 | 0.74 | FDPS (0.46) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL28493935 | 0.74 | FDPS (0.46) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL2908396 | 0.74 | FDPS (0.46) | FDPSSMPD1TSHRTHRBGGPS1 | |
| SCHEMBL4457163 | 0.72 | TSHR (0.57) | FDPSSMPD1TSHRTHRBGGPS1 | |
| Hexane SCHEMBL2911057 | 0.72 | TSHR (0.54) | TSHRTHRBALDH1A1 | |
| Chloroform SCHEMBL19469979 | 0.72 | TSHR (0.42) | FDPSSMPD1TSHRTHRBGGPS1 | |
| Chloroform SCHEMBL459208 | 0.72 | TSHR (0.42) | FDPSSMPD1TSHRTHRBGGPS1 | |
| Chloroform SCHEMBL14672707 | 0.72 | TSHR (0.42) | FDPSSMPD1TSHRTHRBGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302792-B1 | Alkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI SA (FR) | 1994-10-26 | — | — | EP | disclosed |
| US-5215988-A | Treating angina, hypertension, arrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-06-01 | — | — | US | disclosed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4994474-A | Hypotensive agents | SANOFI (FR) | 1991-02-19 | — | — | US | disclosed |
| EP-0302792-A2 | Alkylaminoalkoxyphenyl derivatives, process of preparation and compositions containing the same | SANOFI (FR) | 1989-02-08 | — | — | EP | disclosed |