Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7299796 | 1.00 | TCF4 (0.43) | TCF4CTNNB1KCNH2MAPK1ADRA2A | |
| SCHEMBL7306397 | 0.89 | TCF4 (0.47) | TCF4CTNNB1MAPK1ADRA2AADRA2C | |
| SCHEMBL7306999 | 0.89 | TCF4 (0.48) | TCF4CTNNB1MAPK1PTGS1PTGS2 | |
| SCHEMBL7306992 | 0.89 | TCF4 (0.48) | TCF4CTNNB1MAPK1PTGS1PTGS2 | |
| SCHEMBL7303847 | 0.82 | FNTA (0.44) | TCF4CTNNB1KCNH2MAPK1ADRA2A | |
| SCHEMBL7303850 | 0.82 | FNTA (0.44) | TCF4CTNNB1KCNH2MAPK1ADRA2A | |
| SCHEMBL6000759 | 0.82 | SETD7 (0.49) | TCF4CTNNB1KCNH2MAPK1ADRA2A | |
| SCHEMBL6000763 | 0.82 | SETD7 (0.49) | TCF4CTNNB1KCNH2MAPK1ADRA2A | |
| SCHEMBL7310123 | 0.81 | TCF4 (0.47) | TCF4CTNNB1KCNH2MAPK1ADRA2A | |
| Hydrochloric Acid SCHEMBL7212429 | 0.81 | SETD7 (0.48) | TCF4CTNNB1KCNH2MAPK1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |